I've never read Ayn Rand, only critiques of her writing, and most of those were negative. The Simpsons has made fun of her a few times.
Rand's critics are numerous, from lefties that hate America to conservatives that abhor her atheism, but there is no substitute for doing your own reading and making your own critique. As for The Simpsons, well, I'll just let that statement stand on it's own wobbly legs.
"The beauty of the Second Amendment is that you won't need it until they try to take it away."---Thomas Jefferson