Pictures broadcast by 7 News Belize showed the two main wooden structures at Mr McAfee's compound on the outskirts of Orange Walk Town had been destroyed.
A building manager reportedly called the fire department as a bush fire closed in, but by the time they got there it was too late to stop the blaze.
The property, which was reportedly for sale, was where Mr McAfee was living when his American neighbour Gregory Faull was shot dead in November.
It was subsequently raided by Belize police who found guns and ammunition. Mr McAfee was named as a "person of interest" but not a suspect in the case.
He denied any involvement and claimed he was being persecuted by corrupt authorities.
The fire was quarantined and did not spread to other houses.
This should serve as a warning to update your fire protection.